Accent Folding takes your application and lets it understand that cafe and café are the same word. It goes beyond just a mere language translation that most applications already have in place. It’s possible but be warned.
Be aware that there are a million caveats to accent rules. You will almost certainly get it wrong for somebody, somewhere. Nearly every alphabet has a few extra-special marks that do affect meaning, and, of course, non-Western alphabets have completely different rules.