In terms of repetition and annoyance, yes, the two are very much alike. But they’re fundamentally different in this way: Prefixes give us control of our hacking destiny. In the past, we had to invent a bunch of parser exploits just to get inconsistent implementations to act the same once we found out they were inconsistent. It was a wholly reactive approach. Prefixes are a proactive approach.
via A List Apart – Prefix or Posthack. This is an interesting opinion but I see the logic, eliminates the possibility of broken CSS styles as browsers change and create new standards and abilities.